Crystal structure of a short-chain dehydrogenase/reductase from Burkholderia phymatum in complex with NAD

Alenazi, J.; Mayclin, S.; Subramanian, S.; Myler, P.J.; Asojo, O.A.

doi:10.1107/S2053230X22000218

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

IUCr IT WDC

home archive editors for authors for readers submit subscribe open access

view article

Figure 4
Structural and primary-sequence alignment of SDRs. The SDRs that are compared with BpSDR (PDB entry 5ig2) are the Rv0851c ortholog short-chain dehydrogenase from M. paratuberculosis (PDB entry 3tjr), the 7α-hydroxysteroid dehydrogenase complex (PDB entry 1fmc), Ligl from Sphingobium sp. strain SYK-6 (PDB entry 4yai), clavulanic acid dehydrogenase (PDB entry 2jap) and 17β-hydroxysteroid dehydrogenase type 14 mutant Y253A (PDB entry 6g4l). The secondary-structure elements shown are α-helices (α), 3₁₀-helices (η), β-strands (β) and β-turns (TT). Identical residues are shown in white on a red background and conserved residues are shown in red. This figure was generated using ESPript (Gouet et al., 1999