issue contents

Journal logoIUCrDATA
ISSN: 2414-3146

March 2020 issue

Highlighted illustration

Cover illustration: Crystals of the dimethyl sulfoxide (DMSO) solvate of [1-9-N[alpha]C]-linusorb B3 (Cyclo­linopeptide A; CLP-A; C57H84N9O9·C2H6OS), a cyclic polypeptide were obtained following peptide extraction and purification from flaxseed oil. The cyclic polypeptide or orbitide has nine amino acids (Ile1-Leu2-Val3-Pro4-Pro5-Phe6-Phe7-Leu8-Ile9). The compound has been shown to induce potentially beneficial responses in living organisms. It has demonstrating cytoprotective activity in liver cells by inhibiting cholate uptake and has been shown to have immunosuppressive activity, and no toxicity at high doses. See: Purdy, Spasyuk, Chitanda & Reaney [IUCrData (2020). 5, x200318].

metal-organic compounds


link to html
The title compound consists of a manganese(II) ion that is bonded to four bromide atoms in a tetra­hedral coordination, and a cation based on an imidazolium group with one ethyl and one adamantyl (the simplest diamondoid) group.

link to html
The reaction of ligand 5,7-di­hydro-1H,3H-dithieno[3,4-b:3′,4′-e]pyrazine with CuI lead to the formation of a three-dimensional coordination polymer.

organic compounds


link to html
In the title compound, the pyran ring is in a half-chair conformation. The essentially planar naphthalene ring system forms a dihedral angle of 14.37 (5)° with the fused benzene ring. In the crystal, pairs of mol­ecules are connected into inversion dimers by weak C—H⋯O hydrogen bonds to generate R_{2}^{2}(6) loops.

link to html
In the title compound, the seven-membered ring is in a psuedo-chair conformation. In the crystal, mol­ecules are linked by weak C—H⋯O hydrogen bonds forming layers parallel to (010). In addition, there are weak π–π stacking inter­actions between inversion-related naphthalene ring systems.

link to html
In the title solvate, the tertiary amine adopts a stair-like conformation, with all imine and amine groups forming N—H⋯O and O—H⋯N hydrogen bonds with the lattice methanol mol­ecules.

link to html
The crystal structure of the head-to-head photodimer of indeno­indene, obtained by irradiation of 1-(1-benzo­cyclo­butenyl­idene)benzo­cyclo­butene, is reported.

link to html
In the title compound, he pyran ring is in a half-chair conformation and the fused ring system comprising the benzene and cyclo­hexene rings is essentially planar and forms a dihedral angle of 27.95 (6)° with the other benzene ring. In the crystal, O—H⋯O hydrogen bonds connect the mol­ecules into chains propagating along [001].

link to html
A new quinazolinthione derivative was synthesized, and X-ray diffraction analysis proved the E configuration for the exocyclic double bond in the mol­ecule.

link to html
[1–9-NαC]-Linusorb B3 (Cyclo­linopeptide A) was extracted from flaxseed oil crystals formed in dimethyl sulfoxide. The mol­ecule has four intra­molecular N—H⋯O hydrogen bonds, and the DMSO solvate mol­ecule is bound to the Phe6 amino acid by a fifth N—H⋯O hydrogen bond.

link to html
The title mol­ecule has inversion symmetry, adopting the shape of a St Andrew's cross. It shows dihedral angles between adjacent aryl units of around 50° whereas torsion angles of ca 10° are found along the aryl­ene vinyl­ene path.

link to html
The dihedral angle between the pyrrolo­[1,2-c]pyrimidine ring system and the benzene ring is 80.2 (9)°. In the crystal, inversion dimers linked by pairs of C—H⋯O inter­actions generate R_{2}^{2}(16) loops. Several aromatic π–π stacking inter­actions between the pyrrolo­[1,2-c]pyrimidine rings, as well as separately between the pyrrolo and pyrimidine groups [shortest centroid–centroid separation = 3.5758 (14) Å], help to consolidate the packing.

link to html
In the crystal, mol­ecules of the title compound are linked into (100) sheets by N—H⋯N hydrogen bonds.

link to html
The tandem in situ double Suzuki coupling reaction of a diborated ethyl­ene compound containing electron-withdrawing aromatic ester groups was studied. The major product is derived from the Suzuki coupling involving the boryl group and an aryl­iodide derivative followed by preferential protodeboronation of the second boryl ligand.
Follow IUCr Journals
Sign up for e-alerts
Follow IUCr on Twitter
Follow us on facebook
Sign up for RSS feeds