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July 2023 issue
Cover illustration: A superoxide dismutase V87H mutant from the anhydrobiotic tardigrade Ramazzottius varieornatus strain YOKOZUNA-1 [Sim & Inoue (2023), Acta Cryst. F79, 169–179]. Anhydrobiotic tardigrades are some of the toughest micro-animals and experience severe oxidative stress. They are thought to have potent systems to efficiently eliminate reactive oxygen species including an expanded set of genes for antioxidant proteins such as the ubiquitous superoxide dismutase. These proteins are thought to play an essential role in critical situations such as desiccation, although their functions at the molecular level have yet to be explored. Some terrestrial tardigrades such as R. varieornatus have recently been studied as potential model organisms because of their ability to survive desiccated conditions through anhydrobiosis.
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